Efficacy of Malla Sindoora prepared by adopting new Technology: Pre-Clinical approach

Abstract

Rasoushadhis got popular day by day due to its unique assimilatory organometallic constitution. If Good Rasashastra practice is blended with scientific physico chemical and instrumental gadgets for up-to-date analysis, the drug designing in pharmaceutical field can excel to the top. MallaSindoorais one of the unique Rasa Yoga, with Parada, Gandhaka&Malla prepared by Kupipaka method having indications in Vataroga, Amavata, Visuchika etc. In present study  the evaluation of its Analgesic activity on albino rats is carried out.  Humans share majority of their genes with mice and rats. The physiologies of humans and these animals are very similar. They are susceptible to many of the same health problems as men. Also, the short life span allows animals to be studied throughout their entire life.Thus research on animals is important in understanding diseases and developing ways to prevent them. Also, the pharmaceutical research requires the experimental use of animals for drug control regulatory approvals, as conducting experimental study prior to human trial is mandatory. Even though MallaSindoora is time tested, we need to give a base to understand its analgesic action through in vivo study. Therefore to prepare MallaSindoora by Classical and VMF and systematically observe the pharmaceutical process as well as to accord technological evidences and evaluate analgesic activity in vivo, the present study entitled “Efficacy of MallaSindoora prepared by adopting new technology . A Pre-Clinical approach ” has been undertaken. Objective: To carry out the Analgesic activity of MallaSindoora 1 & 2 on Albino rats by Using Analgesiometer.